49ers 2025 Opponents Synonym. The schedule includes opponents, date, time, and tv network. The san francisco 49ers will receive a slight reprieve in the 2025 season thanks to their abysmal 2024 campaign.

San francisco 49ers 2025 schedule. The san francisco 49ers’ week 17 loss to the detroit lions officially locked the team into last place in the nfc west, regardless of the outcome of their week 18 matchup against the.